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| 2 | 2003
Klinisk Biokemi i Norden
31
nummer af et kit, bliver af GUM tolket som en
variationskoefficient, hvorved effekten af fejlen
på
clinical outcome
undervurderes groft.
GUM er ikke alene overflødig – GUM er direkte ska-
delig.
Hvorfor skal vi dog påtvinges GUM ?
Referencer:
1. Guide to expression of uncertainty in mea-
surement. ISO:
Geneva
1995.
2. Kristiansen J. Description of a generally
applicable model for the evaluation of
uncertainty of measurement in clinical che-
mistry.
Clin Chem Med Lab
2001; 39:920-31.
3. Thienpont LM, van Uytfanghe K, de Leen-
heer AP. Reference measurement systems in
clinical chemistry.
Clin Chem Acta
2002;
323:73-87.
4. http://www.furst.no/norip/
5. Hyltoft Petersen P, Stöckl D, Westgard JO,
Sandberg S, Linnet K, Thienpont L. Models for
combining random and systematic errors.
Assumptions and consequences for different
models.
Clin Chem Lab Med
2001; 39:589-95.
6. Box G, Luceño A. Statistical Control by moni-
toring and feedback adjustment.
John Wiley &
sons
, INC, New York – Chichester – Weinheim
– Brisbane – Singapore – Toronto 1997
7. Thienpont LM, Stöckl D,Kratochvila J,
Friedeck, Budina M. Pilot external quality
assessment survey for post-market vigilance
of in-vitro diagnostic medical devices and
investigation of trueness of participants’
results.
Clin Chem Lab Med
2003; 41:183-6.
8. Kallner A. Quality specifications based on
the uncertainty of measurements.
Scand J
Clin Lab Invest
1999; 59:513-6.
9. Linko S, Örnemark U, Kessel R, Taylor PDP.
Evaluation of uncertainty of measurement
in routine clinical chemistry – Applications
to determination of the substance concen-
tration of calcium and glucose in serum.
Clin Chem Lab Med
2002; 40:391-8.
10. Jørgensen LGM, Stahl M, Brandslund I,
Hyltoft Petersen P, Borch-Johnsen K, de Fine
Olivarius N. Plasma glucose reference inter-
val in a low-risk population 2. Impact of the
new WHO and ADA recommendations on
diagnosis of diabetes mellitus.
Scand J Clin
Lab Invest
2001; 61:181-190.
11. Hyltoft Petersen P, Fraser CG, Kallner A,
Kenny D (eds). Strategies to Set Global Ana-
lytical Quality Specifications in Laboratory
Medicine.
Scan J Clin Lab Invest
1999; 59:
475-585.
12. Hyltoft Petersen P, Brandslund I, Jørgensen
LGM, Stahl M, de Fine Olivarius N, Borch-
Johnsen K. Evaluation of systematic and
random factors in measurements of fasting
plasma glucose as the basis for analytical
quality specifications in the diagnosis of
diabetes. 3. Impact of the new WHO and
ADA recommendations on diagnosis of dia-
betes mellitus.
Scand J Clin Lab Invest
2001;
61:191-204.
