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14
| 1 | 2005
Klinisk Biokemi i Norden
To Lessen Serial Cardiovascular Readmissions and
Death (BATTLE-SCARRED) trial (25).
In summary it seems that the best-documented
clinical application of BNP measurement currently,
is for the emergency diagnosis of HF in patients
presenting with acute dyspnea.
There may be a trend, however, towards increased
use of BNP in the outpatient setting as shown recently
by data from the Clinical Chemistry Department of a
San Diego VA Hospital. While initially most samples
had been sent from the emergency department, the
proportion coming from outpatient departments had
increased from 8% in 2001 to 47% in 2003 (26).
While this propably reflects the potential value
of BNP-guided clinical strategies this value has not
yet been validated extensively in long-term clinical
studies that demonstrate the benefit of this type of
approach.
Reference:
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2. Mark DB, Felker GM. B-type natriuretic peptide
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3. Wang TJ, Larson MG, Levy D, Benjamin EJ,
Leip EP, Omland T, Wolf PA, Vasan RS. Plasma
natriuretic peptide levels and the risk of car-
diovascular events and death. N Engl J Med.
2004;350(7):655-63
4. Cosson S. Usefulness of B-type natriuretic pep-
tide (BNP) as a screen for left ventricular abnor-
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5. Bhalla MA, Chiang A, Epshteyn VA, Kazanegra
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Morrison LK, Chiu A, Gardetto N, Mudaliar S,
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ents with type 2 diabetes mellitus. J Am Coll
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RM, McCord J, Hollander JE, et.al.Impact of age,
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E, Maisel AS. Utility of B-natriuretic peptide
in detecting diastolic dysfunction: comparison
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R, Clopton P, Gardetto N, Morrisey R, Garcia A,
Chiu A. and De Maria A Utility of B-natriuretic
peptide as a rapid, point-of-care test for screen-
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