The first marker to accurately
and simply estimate RRF
status with one serum sample
N Latex Beta-Trace-Protein
The N Latex BTP assay from Siemens Healthcare
is a fast and accurate screening method for
determination of GFR and RRF in serum samples.
Beta Trace Protein determination requires only a
single serum sample that can be obtained during
routine care of dialysis patients.
In patients undergoing dialysis, contribution of
the residual native kidney function, also known as
residual renal function (RRF), is highly associated
with improved outcomes. RRF can be an important
marker for monitoring the decline of kidney
function, predicting mortality, deciding on
peritoneal dialysis versus hemodialysis, and
adjusting the dialysis regimen. Maintenance of
some level of RRF may also improve quality of life
for patients, as it may influence food intake and
diet. An optimized approach to dialysis can also
help to manage costs, because dialysis contributes
significantly to overall healthcare expenditures
The estimation of RRF by BTP measurement may
help support decisions regarding the modality and
frequency of dialysis and thus contribute to better
patient outcomes.
siemens.com/healthineers
BTP is an accurate endogenous marker for GFR
estimation in both general CKD, and pediatric patient
populations as well as in renal transplant receipients.
Estimation of RRF in dialysis patients. RRF is expressed
as average of urinary urea and creatinine clearance.
Adult estimated RRF using BTP:
CL
UREA, CREAT
(ml/min./1,73 m2) = 95 × BTP
-2.16
(x 1.652 if the patient is male)
(BTP = mg/L; RRF = mL/min/1.73m
2
)
CKD-EPI equation using BTP:
eGFR = 55 x BTP-0.695 x 0.998
age
(x 0.899 if the patient is female)
(BTP = mg/L; eGFR = mL/min/1.73 m
2
)
Pediatric estimated GFR using BTP:
eGFR = 10^(1.902 + (0.9515 x LOG(1/BTP)))
