Klinisk Biokemi i Norden · 2 2015
| 21
CD163: a homogenous ectodomain protein
with a dissociable haptoglobin-hemoglobin
binding. Immunobiology 2010;215:406-12.
13. Kneidl J, Løffler B, Erat MC, Kalinka J,
Peters G, Roth J, Barczyk K. Soluble CD163
promotes recognition, phagocytosis and kil-
ling of Staphylococcus aureus via binding of
specific fibronectin peptides. Cell Microbiol
2012;14:914-36
14. Møller HJ, Hald K, Moestrup SK. Characteri-
zation of an enzyme-linked immunosorbent
assay for soluble CD163. Scand J Clin Lab
Invest 2002;62:293-9.
15. Møller HJ, Petersen PH, Rejnmark L, Moes-
trup SK. Biological variation of soluble CD163.
Scand J Clin Lab Invest 2003;63:15-21.
16. Schaer DJ, Schleiffenbaum B, Kurrer M,
Imhof A, Bächli E, Fehr J, et al. Soluble hemo-
globin-haptoglobin scavenger receptor CD163
as a lineage-specific marker in the reactive
hemophagocytic syndrome. Eur J Haematol
2005;74:6-10.
17. Møller HJ, Moestrup SK, Weis N, Wejse C,
Nielsen H, Pedersen SS, et al. Macrophage
serummarkers in pneumococcal bacteremia:
Prediction of survival by soluble CD163. Crit
Care Med 2006;34:2561-6.
18. Møller HJ, Grønbaek H, Schiødt FV, Holland-
Fischer P, Schilsky M, Munoz S, et al; U.S.
Acute Liver Failure Study Group. Soluble
CD163 from activated macrophages predicts
mortality in acute liver failure. J Hepatol
2007;47:671-6.
19. Kazankov K, Barrera F, Møller HJ, Bibby BM,
Vilstrup H, George J, et al. Soluble CD163, a
macrophage activation marker, is indepen-
dently associated with fibrosis in patients with
chronic viral hepatitis B and C. Hepatology
2014;60:521-30.
20. Rode A, Nicoll A, Møller HJ, Lim L, Angus
PW, Kronborg I, et al. Hepatic macrophage
activation predicts clinical decompensation
in chronic liver disease. Gut 2013;62:1231-2.
21. Fjeldborg K, Pedersen SB, M.ller HJ, Christi-
ansen T, Bennetzen M, Richelsen B. Human
adipose tissue macrophages are enhanced but
changed to an anti-inflammatory profile in
obesity. J Immunol Res 2014;2014:309548.
22. Parkner T, Sørensen LP, Nielsen AR, Fischer
CP, Bibby BM, Nielsen S, et al. Soluble CD163:
a biomarker linking macrophages and insulin
resistance. Diabetologia. 2012;55:1856-62.
23. Møller HJ, Frikke-Schmidt R, Moestrup SK,
Nordestgaard BG, Tybjørg-Hansen A. Serum
soluble CD163 predicts risk of type 2 dia-
betes in the general population. Clin Chem
2011;57:291-7.
24. Fjeldborg K, Pedersen SB, Møller HJ, Rask P,
Danielsen AV, Stødkilde-Jørgensen H, Richel-
sen B. Intrahepatic fat content correlates
with soluble CD163 in relation to weight loss
induced by Roux-en-Y gastric bypass. Obesity
(Silver Spring) 2015;23:154-61.
Hästhov (Tussilago farfara). Foto: Henrik Alfthan.
