man kan analysera kvalitetskontroller, ex. kom–
mersiellt tillgängliga kontroller, alt. protein-buf–
fert-saltlösningar av de aktuella komponenterna?
Viktiga frågor närman diskuterar ackreditering!
-
Vem på laboratoriet ansvarar för analys–
verksamheten och fördelningen av läkarnas ar–
betsuppgifter, och har vederbörande kompetens
för sin uppgift?
Litteratur
1.Bos!GJ,ChagantiRSK.Theuseofturnormarkers ingerm
cellmalignancies [Review].HernatalOncol ClinNorth
Am
1994;8(3):573-87.
2. Murphy BA, Motzer RJ, Mazumdar M, Vlamis V,
Nisselbaum J, Bajorin D, Bos! GJ. Serum turnor marker
decline is an ear!y predietar of treatment outcome in germ
cell turnor patients trealed with cisplatin and ifosfamide
salvage chemotherapy. Cancer 1994;73:252_0-6.
.
3.BassettoMA,FrancechiT, LenottiM, Par1seG, Panchen
F, Sabbioni R, et al. AFP andHCG in germ cell tumors. Int
J Bio!Markers 1994;9:29-32.
4. Boscato LM, Stuart MC. Incidence and specificity of
interference in two-site immunoassays. Clin Chem
1986;32:1491-5.
5. Weber TH, Käpyaho Kl, Tanner P. Endogenous
interference in immunoassays inclinical chemistry.ScandJ
Clin Lab Invest 1990;50(Suppl201):77-82.
6.NahmMH,HoffmanJW.Heteroantibody: phantomofthe
immunoassay [Editorial].Clin Chem 1990;36:829.
7.KohseKP,WisserH. Antibodies as a sourceofanalytical
errors. J Clin ChemClin Biochem 1990;28:881-92.
8. B!1lrmer OP. Immunoassays for carcinoembryonic anti–
gen [Dissertation]. Oslo: The Norwegian Cancer Society,
1992:1-103.
9. AakvaagA, LeskinenE, Lindstedt G,Möller J,
N~berg
A, Weber T. Kits for the quantitative assay of chonomc
gonadotrophin. Scand J Clin Invest 1988;48:299-302.
10. Kaczynski J, Jagenburg R, Lindstedt G,Wallerstedt S.
Markedly increased alpha-fetoprotein concentration in se-
KliniskKemi
i
Norden
2,
1995
rum in alcoholic liver desease: malignant turnor or
nonneoplastic changes? ClinChem 1992;38:710-6.
11. Dahlmann N, Hartlapp
JH.
Chemotherapy of a patient
because of spuriously elevated alpha-fetoprotein levels.
KlinWschr 1989;67:408-12.
12.DahlmannN, BidlingmaierF.Circulating antibodies to
mousemonoclonal imrnunoglobulins eaused false-positive
resulls ina two-siteassay foralpha-fetoprotein [Letter].Clin
Chem 1989;35:2339.
13.HedenborgG, PetterssonT, CarlströmA. Heterophilic
antibodies eausing falsely raised thyroid-stimulating–
hormone result. Lancet 1979;ii:755.
14.LindstedtG,GanrothP-0,GrubbA,RonquistG,Venge
P.Specialistexamen ikliniskkemi.Frivilligexamination för
ökad kompetens. Läkartidningen 1993;90:599-602.
15. Lindstedt G, Lundberg P-A, Hedman LA. Circulating
choriogonadotrophin
~
subunit in a
pa~ent
with primary
amenorrhea and embryonal ovarian carcmoma. Chn Ch1m
Acta 1980;104:195-200.
16. Lindstedt G, Lundberg P-A, Janson PO, Thorhum J.
Biochemical diagnosis of ectopic pregnancy [Editorial re–
view]. Scand J ClinLab lnvest 1982;42:201-10.
17.SallerB,Clara
R.
SpöttlG,SiddleK,MannaK.Testicular
cancer secretes intact human choriogonadotrophin (hCG)
and its free
~-subunit:
evidence that hCG (
+hCG-~)
assays
are themost reliable indiagnosis and follow-up. ClinChem
1990;36:234-9.
18.FossåSD,OusS,ÅbyholmT,NormanN,LoebM. Post–
treatment fertility in patients with testicular cancer. II.
Influence of cis-platin-based combination chemotherapy
and of retroperitoneal surgery on hormone and sperm cell
production. Br J Urol1985;57:210-4.
19. Petersen PM, Hansen SW, Giwercman A, R!1lrth M,
Skakkebaek NE.Dose-dependent impairment of testicular
function in patients treated with cisplatin-based chemo–
therapy for germ cell cancer. Ann Oncol1994;5:355-8.
20.BoshoffC,BegentRHJ, OliverRTD, RustinGJ,News–
lands ES, Andrews R, et al. Secondary tumours following
etoposide-containing therapy for germ cell cancer. Ann
Oncol 1995;6:35-40.
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