Klinisk Biokemi i Norden · 4 2019
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vil være forståelsen af de underliggende mekanismer
bag mindre forstyrrelser i thyroidea funktionen hos
gravide samt betydningen af thyroidea autoimmu-
nitet
per se.
Disputatsen er baseret på
følgende artikler:
Paper I:
Hyperthyroidism incidence fluctuates
widely in and around pregnancy and is at variance
with some other autoimmune diseases: a Danish
population-based study. J Clin Endocrinol Metab
2015;100:1164–71.
Paper II:
Hypothyroidism incidence in and around
pregnancy: a Danish nationwide study. Eur J Endo-
crinol 2016;175:387-93.
Paper III:
Maternal thyroid disease in the Danish
National Birth Cohort: prevalence and risk factors.
Eur J Endocrinol 2016;174:203-12.
Paper IV:
Dynamics and predictors of serum TSH
and fT4 reference limits in early pregnancy: a study
within the Danish National Birth Cohort. J Clin
Endocrinol Metab 2016;101:2484-92.
Paper V:
Early pregnancy thyroid function test
abnormalities in biobank sera from women clinically
diagnosed with thyroid dysfunction before or after
pregnancy. Thyroid 2017;27:451-59.
Paper VI:
Smoking reduces the risk of hypothy-
roidism and increases the risk of hyperthyroidism:
evidence from 450,842 mothers giving birth in Den-
mark. Clin Endocrinol 2014;80:307-14.
Paper VII:
Maternal thyroid function in early preg-
nancy and child neurodevelopmental disorders:
a Danish nationwide case-cohort study. Thyroid
2018;28:537-46.
Paper VIII:
Maternal thyroid function in early
pregnancy and neuropsychological performance of
the child at 5 years of age. J Clin Endocrinol Metab
2018;103:660-70.
Paper IX:
Birth defects after early pregnancy use of
antithyroid drugs: a Danish nationwide study. J Clin
Endocrinol Metab 2013;98:4373-81.
Paper X:
Severity of birth defects after Propyl
thiouracil exposure in early pregnancy. Thyroid
2014;24:1533-40.
Paper XI:
Antithyroid drug side effects in the popu-
lation and in pregnancy. J Clin Endocrinol Metab
2016;101:1606-14.
Paper XII:
Birth defects after use of antithyroid drugs
in early pregnancy: a Swedish nationwide study. Eur
J Endocrinol 2017;177:369-78.
Disputatsen kan rekvireres ved henvendelse til forfat-
teren. Forsvaret fandt sted den 21. juni 2019.
Foto: Henrik Alfthan.
