Klinisk Biokemi i Norden · 1 2015
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Figure 2.
Variation in D-dimer
concentration (mg/L), MoM
(D-dimer/median) and lnMoM
as function of time for 18
healthy pregnant women
during pregnancy and the post-
partum period (Figures 2A, B
and C). Each line represents the
trajectory of D-dimer concen-
tration for individual women.
The shaded area encloses the
range of mean ± 2SD D-dimer
concentration for pregnancy
and the postpartum period.
*Week of blood sampling in
pregnancy, †days after delivery,
‡weeks after delivery (Figures
2A, B and C). Reprinted from
Kristoffersen AH et al. A model
for calculating the within-
subject biological variation and
likelihood ratios for analytes
with a time-dependent change
in concentrations; exemplified
with the use of D-dimer in
suspected venous thrombo-
embolism in healthy pregnant
women. Ann Clin Biochem
2012;49:561-9. Reprinted with
permission of SAGE.
