Klinisk Biokemi i Norden Nr 2, vol. 28, 2016 - page 18

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Klinisk Biokemi i Norden · 2 2016
Part 3
Table 4. Deviations from”0 – sample” which allows 95.5 % of the results to fulfill goals
Component
CV %
Analytical
Critical
level
Clinical pre-analytical
deviation
Total CV for
deviation(%)
Allowed deviation (%)
between 0 – sample
and test sample 95.5%
results within ±2 SD
Concentra-
tion
CI 95.5 %
CV %,
B – Hemoglobin
0,8
7,6
0,62
4,0
4,2
8,0*
(B)Erythr – MCV
1
89
4,24
1,9
2,4
4,8
B – Leucocytes
1,8
7,2
2,33
16,0
16,2
32,3
B – Neutrophils
2,2
5
2,41
23,9
24,1
48,3
B – Eosinophils
6,9
1,95
1,21
29,4
30,9
61,9
B – Lymfocytes
3,7
3,27
0,99
14,3
15,2
30,4
B – Monocytes
10,3
2,17
1,25
24,8
28,8
57,6
B – Trombocytes
1,6
506
130,91
12,7
12,9
25,9
B – Reticulocytes
2,5
75,1
23,72
15,4
15,8
31,6
B – Hematocrit
2,1
0,47
0,05
3,8
4,8
9,6
Table 4: Critical level is the level at which the maximal allowed deviation is defined. Clinical acceptable pre-analytical devia-
tion (95.5% CI) is given as a concentration in reported units and as CV%. CV% analytical is the imprecision in the laborato-
ries. Total CV for deviation is the combined CV – analytical for both 0-sample and the test sample and the CV% of accepted
deviation. Maximal allowed deviation is the 95.5% CI limits for difference between 0-sample and test sample which fulfill the
goals at the critical level.
*Clinical acceptable pre-analytical deviation is an estimate
Table 4a. No. of results which fulfill the goals.
Component
Percentage of results which fulfill the demand on allowed deviation
Second transport
First transport next day
B – Hemoglobin
100
100
(B)Erythr – MCV
100
7,3
B – Leucocytes
100
100
B – Neutrophils
100
100
B – Eosinophils
96,7
100
B – Lymfocyts
100
100
B – Monocytes
100
100
B – Trombocytes
100
100
B – Reticulocytes
96,7
100
B – Hematocrit
100
29,2
Table 4a show how many samples which fulfill the demand on allowed deviation in % for each group of tubes.
1...,8,9,10,11,12,13,14,15,16,17 19,20,21,22,23,24,25,26,27,28,...52
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